Missouri's 6 metropolitan areas offer diverse rental options across the state, making them among the best places to live in the Midwest. Kansas City and St. Louis anchor the state as major urban centers. The Kansas City metro area features neighborhoods like the Power & Light District and Country Club Plaza with metropolitan amenities. St. Louis showcases architectural heritage, innovation districts like Cortex, and the MetroLink system connecting its neighborhoods. The mid-sized metropolitan areas of Springfield and Columbia provide alternatives with lower costs of living while maintaining robust amenities. Springfield combines urban conveniences with natural beauty in the Ozarks, offering downtown lofts and healthcare employment opportunities. Columbia's university presence creates an active rental market with numerous cultural offerings. Completing Missouri's metropolitan landscape are Joplin, St. Joseph, and Cape Girardeau, each with its own character. Joplin features updated housing stock following the 2011 tornado, alongside manufacturing and healthcare employment opportunities. St. Joseph showcases 19th-century architecture with affordable rental properties, while Cape Girardeau offers a Mississippi River setting and university presence. Explore the best places to live in Missouri and find your new home.