Pennsylvania Neighborhoods S
- Salem Square (7)
- Scott Township (7)
- Shade Gap (3)
- Shadyside (41)
- Sheraden (5)
- Shiloh (5)
- Sixth Ward (3)
- Slatington Historic District (5)
- Society Hill (19)
- South Ardmore (9)
- South Duquesne Heights (4)
- South East Hills (2)
- South Easton (8)
- South Harrisburg (1)
- South Philadelphia East (31)
- South Philadelphia West (63)
- South Shore (3)
- South Side (30)
- South Suburban Erie (9)
- Southeast Community (3)
- Southeast Erie (3)
- Southeast Reading (8)
- Southside (5)
- Southside Flats (123)
- Southside Slopes (40)
- Southside-Lehigh (40)
- Southwest Center City (75)
- Southwest Reading (7)
- Southwest York (11)
- Spring Hill City View (7)
- Spring Ridge (2)
- Springetts Manor-Yorklyn (3)
- Spruce Hill (71)
- Spry (3)
- Squirrel Hill North (20)
- Squirrel Hill South (36)
- St Mary (2)
- St Mary's (7)
- Stadium District (4)
- Stanton Heights (14)
- State College South (1)
- Stevens (4)
- Stonybrook-Wilshire (3)
- Strasburg/Paradise/Gap (1)
- Strip District (16)
- Sun Hill (5)
- Sun Village (3)
- Swisshelm Park (1)
- Swissvale (10)
- Swoyersville (2)