Pennsylvania Neighborhoods S
- Salem Square (5)
- Scott Township (7)
- Sewickley Heights (1)
- Shade Gap (1)
- Shadyside (44)
- Sheraden (7)
- Shiloh (5)
- Slatington Historic District (2)
- Society Hill (27)
- South Ardmore (15)
- South Duquesne Heights (4)
- South East Hills (2)
- South Easton (9)
- South Harrisburg (3)
- South Philadelphia East (24)
- South Philadelphia West (65)
- South Shore (5)
- South Side (26)
- South Suburban Erie (8)
- Southeast Community (5)
- Southeast Erie (5)
- Southeast Reading (3)
- Southside (4)
- Southside Flats (97)
- Southside Slopes (27)
- Southside-Lehigh (29)
- Southwest Center City (65)
- Southwest Reading (4)
- Southwest York (5)
- Spring Hill City View (4)
- Springetts Manor-Yorklyn (3)
- Spruce Hill (105)
- Spry (2)
- Squirrel Hill North (21)
- Squirrel Hill South (54)
- St Lawrence (1)
- St Mary (1)
- St Mary's (3)
- Stadium District (2)
- Stanton Heights (4)
- State College South (1)
- Stevens (4)
- Stonybrook (1)
- Stonybrook-Wilshire (4)
- Strip District (18)
- Sun Hill (4)
- Sun Village (3)
- Swisshelm Park (1)
- Swissvale (11)