Barrios de Misuri S
- Santa Fe
- Sappington
- Scarritt Point
- Self Help Neighborhood Council
- Shaw
- Sherrydale
- Sherwood Estates
- Skinker DeBaliviere
- Soulard
- South Blue Valley
- South Crysler
- South Hyde Park
- South Plaza
- South Town Fork Creek
- Southern
- Southern Hills
- Southmoreland
- Southwest Garden
- St John
- St Louis Hills
- St Louis Place
- Sunset Hill
- Sycamore