Barrios de Pensilvania S
- Salem Square
- Schnecksville Historic District
- Scott Township
- Shiloh
- Sixth Ward
- Slatington Historic District
- Society Hill
- South Ardmore
- South Duquesne Heights
- South Easton
- South Harrisburg
- South Philadelphia East
- South Philadelphia West
- South Shore
- South Side
- South Suburban Erie
- Southeast Community
- Southeast Erie
- Southeast Reading
- Southside Flats
- Southside Slopes
- Southside-Lehigh
- Southwest Center City
- Southwest Reading
- Southwest York
- Spring Hill City View
- Springetts Manor-Yorklyn
- Spruce Hill
- Spry
- Squirrel Hill North
- Squirrel Hill South
- St Mary
- Stadium District
- Stanton Heights
- Stevens
- Stonybrook-Wilshire
- Strip District
- Sun Village
- Swoyersville