Located in South Carolina's thriving Upstate region between Greenville and Spartanburg, Duncan has grown from a small mill town into a significant economic hub, anchored by the North American headquarters of international manufacturers Staubli and Dräxlmaier Group. The town's strategic position along Interstate 85 and U.S. Route 29 puts both Greenville and Spartanburg's business districts within an easy 20-minute drive. Duncan's established neighborhoods near Main Street (SC 290) feature rental houses with tree-lined streets, while newer developments around the Middle Tyger River and River Ridge business corridor offer spacious home options. Three-bedroom houses in Duncan rent for an average of $1,607 monthly. Residents enjoy quick access to the Westgate Mall area, and the town's location places both the Blue Ridge Mountains' recreational opportunities and the Greenville-Spartanburg International Airport within a 30-minute drive.