Nestled along the Milwaukee River 20 miles north of Milwaukee, Grafton blends its rich manufacturing heritage with a vibrant downtown district. The eastern section near Interstate 43 serves as a commercial center, anchored by Aurora Medical Center and various retail destinations, while the historic downtown area features locally-owned shops and restaurants alongside the scenic riverfront.

Rental houses in established neighborhoods near Centennial Park and the downtown river district provide convenient access to the Ozaukee Interurban Trail and riverside amenities. The Cedar Creek area offers proximity to shopping and dining options, while the neighborhoods surrounding Lime Kiln Park blend privacy with outdoor recreation access. Residents enjoy a 25-minute average commute to Milwaukee via I-43, with additional transport options including the Ozaukee County Express bus service. The village's location provides quick access to major employers in healthcare, manufacturing, and retail sectors, with Aurora Medical Center, Kapco, and several other large companies maintaining significant operations in the area. With average rental rates remaining competitive compared to Milwaukee proper, Grafton combines small-town charm with convenient access to city amenities.