Depew, NY began as a railroad hub in 1892 and still maintains its connection to its transportation roots with the Buffalo-Depew Amtrak station serving as the main train station for the Buffalo area. This village of just over 15,000 residents straddles the towns of Lancaster and Cheektowaga, offering renters a small-town atmosphere while being just 11 miles east of downtown Buffalo. The average rent in Depew is $1,202, slightly higher than some neighboring communities but still more affordable than the Buffalo metro average.

Rental options in Depew include boutique apartment communities and single-family homes, many with character and charm reflecting the area's 130-year history. The village's location at the intersection of several major highways (including Transit Road and Broadway) makes it convenient for professionals commuting to Buffalo, Lancaster, or Cheektowaga. With a median household income of $66,521, Depew provides comfortable living spaces with easy access to urban amenities.

Depew combines practical conveniences with local attractions. The Transit Road corridor provides shopping and dining options, while nearby Cheektowaga Town Park and Como Lake Park in Lancaster offer outdoor recreation. The village's railroad heritage is evident in its layout and architecture, giving neighborhoods a distinctive character. For commuters, the village's strategic location and transportation connections make it an appealing option for those who want to live near — but not in — Buffalo's busier urban center.